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Antigenic Specificity | SPPL2B - N-terminal region |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | cow, dog, guinea pig, horse, human, mouse, porcine, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Immunohistochemistry (IHC), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This is a rabbit polyclonal antibody against SPPL2B. It was validated on Western Blot and immunohistochemistryTarget Description: SPPL2B is a member of the GXGD family of aspartic proteases. The GXGD proteases are transmembrane proteins with two conserved catalytic motifs localized within the membrane-spanning regions. This enzyme localizes to endosomes, lysosomes, and the plasma membrane. It cleaves the transmembrane domain of tumor necrosis factor alpha to release the intracellular domain, which triggers cytokine expression in the innate and adaptive immunity pathways. |
Immunogen | Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human SPPL2B |
Other Names | [signal peptide peptidase-like 2B isoform 3; Signal peptide peptidase-like 2B; signal peptide peptidase-like 2B; signal peptide peptidase like 2B; Intramembrane protease 4; IMP-4; Presenilin-like protein 1] |
Gene, Accession # | [SPPL2B], Gene ID: 56928, NCBI: NP_001070706, UniProt: Q8TCT7 |
Catalog # | MBS3207616 |
Price | $365 |
Order / More Info | SPPL2B - N-terminal region Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |