IDDM12 (N-term), 50-78 Antibody from MYBIOSOURCE INC.
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|---|---|
| Antigenic Specificity | IDDM12 (N-term), 50-78 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.08 mL, 0.4 mL |
| Concentration | vial concentration: 0.26 |
| Applications | Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This IDDM12 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 50-78 amino acids from the N-terminal region of human IDDM12. CTLA4 is a member of the immunoglobulin superfamilyand encodes a protein which transmits an inhibitory signal to Tcells. The protein contains a V domain, a transmembrane domain, anda cytoplasmic tail. Alternate transcriptional splice variants,encoding different isoforms, have been characterized. Themembrane-bound isoform functions as a homodimer interconnected by adisulfide bond, while the soluble isoform functions as a monomer.Mutations in this gene have been associated with insulin-dependentdiabetes mellitus, Graves disease, Hashimoto thyroidi |
| Immunogen | n/a |
| Other Names | [Cytotoxic T-lymphocyte protein 4; Cytotoxic T-lymphocyte-associated antigen 4; CTLA-4; CD152; CTLA4; CD152] |
| Gene, Accession # | [CTLA4], Gene ID: 1493, NCBI: NP_001032720.1, UniProt: P16410 |
| Catalog # | MBS9204506 |
| Price | $165, $370 |
| Order / More Info | IDDM12 (N-term), 50-78 Antibody from MYBIOSOURCE INC. |
| Product Specific References | Liu, Y., et al. Hum. Immunol. 71(11):1141-1146(2010) Andersen, M.K., et al. Diabetes Care 33(9):2062-2064(2010) Azarpira, N., et al. Exp Clin Transplant 8(3):210-213(2010) Liu, G., et al. Nan Fang Yi Ke Da Xue Xue Bao 30(8):1838-1840(2010) Oaks, M.K., et al. Cell. Immunol. 201(2):144-153(2000) |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
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