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Antigenic Specificity | HIST1H3A |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. This histone is only present in mammals and is enriched in acetylation of Lys-15 and dimethylation of Lys-10 (H3K9me2). |
Immunogen | Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-136 of human HIST1H3A (NP 003520.1). |
Other Names | [H3/A; H3FA] |
Gene, Accession # | [HIST1H3A], NCBI: NP_003520.1, UniProt: P68431 |
Catalog # | MBS8547270 |
Price | $280 |
Order / More Info | HIST1H3A Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |