UCHL1 Antibody from MYBIOSOURCE INC.
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|---|---|
| Antigenic Specificity | UCHL1 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | affinity purified |
| Size | 0.1 mL |
| Concentration | n/a |
| Applications | Western Blot (WB), Immunohistochemistry (IHC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Protein ubiquitination and deubiquitination are reversible processes catalyzed by ubiquitinating enzymes (UBEs) and deubiquitinating enzymes (DUBs) (1, 2). DUBs are categorized into 5 subfamilies: USP, UCH, OTU, MJD, and JAMM. UCHL1, UCHL3, UCHL5/UCH37, and BRCA-1-associated protein-1 (BAP1) belong to the UCH family of DUBs, which all posses a conserved catalytic domain (UCH domain) of about 230 amino acids. UCHL5 and BAP1 have unique extended C-terminal tails. UCHL1 is abundantly expressed in neuronal tissues and testes, while UCHL3 expression is more widely distributed (3, 4). Although UCHL1 and UCHL3 are the most closely related UCH family members with about 53% identity, their biochemical properties differ in that UCHL1 binds monoubiqui |
| Immunogen | Immunogen: Recombinant protein of human UCHL1 Storage Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Other Names | [PARK5; PGP9.5; Uch-L1] |
| Gene, Accession # | [UCHL1], Gene ID: 7345, NCBI: NP_004172.2, UniProt: P09936 |
| Catalog # | MBS8501262 |
| Price | $310 |
| Order / More Info | UCHL1 Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Nijman, S.M. et al. (2005) Cell 123, 773-86. 2. Nalepa, G. et al. (2006) Nat Rev Drug Discov 5, 596-613. 3. Leroy, E. et al. (1998) Nature 395, 451-2. 4. Kurihara, L.J. et al. (2001) Hum Mol Genet 10, 1963-70. 5. Osaka, H. et al. (2003) Hum Mol Genet 12, 1945-58. 6. Wada, H. et al. (1998) Biochem Biophys Res Commun 251, 688-92. 7. Kwon, J. (2007) Exp Anim 56, 71-7. 8. Suzuki, M. et al. (2009) Endocrinology 150, 5230-9. 9. Butterworth, M.B. et al. (2007) J Biol Chem 282, 37885-93. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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