CD11/CD18 [24] Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityCD11/CD18 [24]
Clone[24]
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG1
Formatfluorescein (FITC) conjugate
Size0.05 mL
Concentration1mg/ml
ApplicationsFlow Cytometry (FC/FACS), Immunocytochemistry (ICC), Immunofluorescence (IF)
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DescriptionThis antibody recognises integrin alpha L,M,X/Beta 2 (CD11/CD18). Integrins are heterodimeric cell surface receptors composed of alpha and beta subunits which mediate cell-cell and cell-extracellular matrix attachments. Integrin beta2 (CD18) associates with integrin alpha L (CD11a) to form the leukocyte function-associated antigen-1 (LFA-1) with integrin alpha M (CD11b) to form Complement Receptor 3 (CR3) and with integrin alpha X (CD11c) to form Complement Receptor 4 (CR4). Each integrin receptor can bind various Intercellular adhesion molecules (ICAMs). Aberrant integrin expression has been found in many epithelial tumours. Changes in integrin expression have been shown to be important for the growth and early metastatic capacity of melan
ImmunogenImmunogen: Fibronectin-purified human monocytes
Other Namesn/a
Gene, Accession #[CD11/CD18]
Catalog #MBS375382
Price$455
Order / More InfoCD11/CD18 [24] Antibody from MYBIOSOURCE INC.
Product Specific ReferencesHogg N, et al. An anti-human monocyte/macrophage monoclonal antibody, reacting most strongly with macrophages in lymphoid tissue. Cell Immunol. 1985. 92(2):247-53. PMID:2581704 http://www.ncbi.nlm.nih.gov/pubmed/2581704
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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