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Antigenic Specificity | Human Transcription elongation factor B polypeptide 2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | SIII, also known as elongin, is a general transcription elongation factor that increases the RNA polymerase II transcription elongation past template-encoded arresting sites. Subunit A is transcriptionally active and its transcription activity is strongly enhanced by binding to the dimeric complex of the SIII regulatory subunits B and C (elongin BC complex). The elongin BC complex seems to be involved as an adapter protein in the proteasomal degradation of target proteins via different E3 ubiquitin ligase complexes, including the von Hippel-Lindau ubiquitination complex CBC(VHL). By binding to BC-box motifs it seems to link target recruitment subunits, like VHL and members of the SOCS box family, to Cullin/RBX1 modules that activate E2 ubiq |
Immunogen | Immunogen: Recombinant human Transcription elongation factor B polypeptide 2 protein(1-118aa) Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-23407 / sc-23406 / sc-11447 |
Other Names | [Elongin 18 kDa subunit; Elongin-B; EloB; RNA polymerase II transcription factor SIII subunit B; SIII p18; TCEB2], [TCEB2; TCEB2; ELOB; SIII; EloB] |
Gene, Accession # | [TCEB2], Gene ID: 6923, NCBI: NP_009039.1, UniProt: Q15370 |
Catalog # | MBS1497891 |
Price | $120, $160 |
Order / More Info | Human Transcription elongation factor B polypeptide 2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |