PAK2 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityPAK2
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formataffinity purified
Size0.1 mL
Concentrationn/a
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
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DescriptionPAK2, also named as PAK65, PAKgamma, p58, PAK-2p27, PAK-2p24 and C-t-PAK2, belongs to the protein kinase superfamily, STE Ser/Thr protein kinase family and STE20 subfamily. PAK2 acts on a variety of targets. PAK2 catalyzes the reaction: ATP + a protein = ADP + a phosphoprotein. PAK2 phosphorylates ribosomal protein S6, histone H4 and myelin basic protein. Full length PAK 2 stimulates cell survival and cell growth. The process is, at least in part, mediated by phosphorylation and inhibition of pro-apoptotic BAD. Caspase-activated PAK-2p34 is involved in cell death response, probably involving the JNK signaling pathway. Cleaved PAK-2p34 seems to have a higher activity than the CDC42-activated form. The antibody has no cross reaction to PAK1 a
ImmunogenImmunogen: Recombinant protein of human PAK2 Storage Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Other Names[PAK65; PAKgamma]
Gene, Accession #[PAK2], Gene ID: 5062, NCBI: NP_002568.2, UniProt: Q13177
Catalog #MBS8500228
Price$310
Order / More InfoPAK2 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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