ICOS-L/ICOS Ligand/B7RP-1 (Immuno-Oncology Target) Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-ICOS-L/ICOS Ligand/B7RP-1 (Immuno-Oncology Target) antibody, protein, ELISA kits.
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| Antigenic Specificity | ICOS-L/ICOS Ligand/B7RP-1 (Immuno-Oncology Target) |
| Clone | [ICOSL/3111] |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG1, kappa |
| Format | purified |
| Size | 0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA & Azide at 1mg/ml) |
| Concentration | n/a |
| Applications | ELISA (EIA), Flow Cytometry (FC/FACS), Immunofluorescence (IF), Immunohistochemistry (IHC) Paraffin |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This MAb recognizes a protein of 36kDa, identified as ICOS-L. It is a ligand for the ICOS receptor that initiates T and B cell proliferation and cytokine secretion. ICOS-L interactions play an essential role in T cell-dependent B cell activation in peripheral lymphoid organs such as spleen and lymph nodes. ICOS-L protein is present in myeloid leukocytes, and by Northern blot there are 2.4, 3.0, and 7.0 kb transcripts in brain, heart, kidney, and liver, with lower expression in colon and thymus, and a 1.1 kb transcript in leukocytes. Tumor necrosis factor alpha (TNF), granulocyte-macrophage colony-stimulating factor (GM-CSF) and interleukin-4 (IL-4) enhance its expression. LPS-induced up-regulation of ICOS-L is dependent on the MyD88-depende |
| Immunogen | Immunogen: Recombinant fragment of human ICOSLG (B7RP-1) protein (around aa 23-149) (exact sequence is proprietary) |
| Other Names | [B7 homolog 2 (B7H2); B7 like protein Gl50; B7 related protein 1 (B7RP1); CD275; CD275 antigen; GL50; ICOS LG; ICOS ligand (ICOSL); Inducible T cell co stimulator ligand; LICOS; Transmembrane protein B7 H2 ICOS ligand] |
| Gene, Accession # | [ICOSLG], Gene ID: 23308, NCBI: O75144.2, UniProt: O75144 |
| Catalog # | MBS4380902 |
| Price | $190, $340, $340 |
| Order / More Info | ICOS-L/ICOS Ligand/B7RP-1 (Immuno-Oncology Target) Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Cao, Y., et al. 2018. Expression of B7-H2 on CD8 T cells in colorectal cancer microenvironment and its clinical significance. Int Immunopharmacol 56: 128-13. 2. Yoshinaga, S.K., et al. 1999. T cell co-stimulation through B7RP-1 and ICOS. Nature 402: 827-832. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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