ITGA4 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityITGA4
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatantigen affinity purified
Size0.06 mL, 0.12 mL, 0.2 mL
Concentration1mg/mL
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC)
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DescriptionIntegrins are alpha/beta heterodimeric cell surface receptors that play a pivotal role in cell adhesion and migration, as well as in growth and survival (1, 2). The integrin family contains at least 18 alpha and 8 beta subunits that form 24 known integrins with distinct tissue distribution and overlapping ligand specificities (3). Integrins not only transmit signals to cells in response to the extracellular environment (outside-in signaling), but also sense intracellular cues to alter their interaction with the extracellular environment (inside-out signaling) (1, 2). A pair of important alpha4 integrins, alpha4beta1 and alpha4beta7, interact with VCAM-1, fibronectin, and MAdCAM-1 at cell adhesions (3). Gene knockout and antibody blocking re
ImmunogenImmunogen: Recombinant protein of human ITGA4 Observed Molecular Weight: 115kDa
Other Names[ITGA4; CD49D; IA4; MGC90518]
Gene, Accession #[ITGA4], Gene ID: 3676, NCBI: AAH80190.1
Catalog #MBS2519915
Price$150, $225, $360
Order / More InfoITGA4 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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