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Antigenic Specificity | ITGA4 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.06 mL, 0.12 mL, 0.2 mL |
Concentration | 1mg/mL |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Integrins are alpha/beta heterodimeric cell surface receptors that play a pivotal role in cell adhesion and migration, as well as in growth and survival (1, 2). The integrin family contains at least 18 alpha and 8 beta subunits that form 24 known integrins with distinct tissue distribution and overlapping ligand specificities (3). Integrins not only transmit signals to cells in response to the extracellular environment (outside-in signaling), but also sense intracellular cues to alter their interaction with the extracellular environment (inside-out signaling) (1, 2). A pair of important alpha4 integrins, alpha4beta1 and alpha4beta7, interact with VCAM-1, fibronectin, and MAdCAM-1 at cell adhesions (3). Gene knockout and antibody blocking re |
Immunogen | Immunogen: Recombinant protein of human ITGA4 Observed Molecular Weight: 115kDa |
Other Names | [ITGA4; CD49D; IA4; MGC90518] |
Gene, Accession # | [ITGA4], Gene ID: 3676, NCBI: AAH80190.1 |
Catalog # | MBS2519915 |
Price | $150, $225, $360 |
Order / More Info | ITGA4 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |