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Antigenic Specificity | CREB (phospho-Ser133) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | n/a |
Isotype | n/a |
Format | unconjugated |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This antibody detects endogenous human, mouse, and rat CREB only when phosphorylated at serine 133. CREB (cAMP response element-binding protein) is a cellular transcription factor. It binds to certain DNA sequences called cAMP response elements (CRE), thereby increasing or decreasing the transcription of the downstream genes. Genes whose transcription is regulated by CREB include: c-fos, BDNF, tyrosine hydroxylase, numerous neuropeptides (such as somatostatin, enkephalin, VGF, corticotropin-releasing hormone), and genes involved in the mammaliancircadian clock (PER1, PER2). |
Immunogen | Antigen: Peptide sequence that includes phosphorylation site of serine 133 (R-P-S(p)-Y-R) derived from human CREB and conjugated to KLH. |
Other Names | [cyclic AMP-responsive element-binding protein 1 isoform A; Cyclic AMP-responsive element-binding protein 1; cyclic AMP-responsive element-binding protein 1; cAMP responsive element binding protein 1], [CREB1; CREB1; CREB; CREB-1; CREB-1; cAMP-responsive element-binding protein 1] |
Gene, Accession # | [CREB], Gene ID: 1385, NCBI: NP_004370.1, UniProt: P16220 |
Catalog # | MBS191064 |
Price | $340 |
Order / More Info | CREB (phospho-Ser133) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |