LARP7 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityLARP7
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatpeptide affinity purified
Size0.1 mL, 0.2 mL
Concentration1mg/ml
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC)
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DescriptionSpecificity: LARP7 antibody detects endogenous levels of LARP7. Function: Negative transcriptional regulator of polymerase II genes, acting by means of the 7SK RNP system. Within the 7SK RNP complex, the positive transcription elongation factor b (P-TEFb) is sequestered in an inactive form, preventing RNA polymerase II phosphorylation and subsequent transcriptional elongation.Subunit Structure: Integral part of the 7SK RNP complex (PubMed:18483487). Specifically binds to the highly conserved 3'-terminal U-rich stretch of 7SK RNA (PubMed:18483487). On stimulation, remains associated with 7SK RNA, whereas P-TEFb is released from the complex (PubMed:18483487). Interacts with METTL16 (PubMed:29051200).
ImmunogenImmunogen: A synthesized peptide derived from human LARP7. Subcellular Location: Nucleus > Nucleoplasm. Predicted Cross Reactivity: Pig, Zebrafish, Bovine, Horse, Sheep, Rabbit, Dog, Chicken, Xenopus Similarity: Pig (83%), Zebrafish (92%), Bovine (100%), Horse (100%), Sheep (100%), Rabbit (100%), Dog (100%), Chicken (100%), Xenopus (92%)
Other Names[DKFZp564K112; HDCMA18P; La related protein 7; La ribonucleoprotein domain family member 7; La ribonucleoprotein domain family member 7; La-related protein 7; LARP 7; larp7; LARP7_HUMAN; MGC104360; P TEFb interaction protein for 7SK stability; P-TEFb-interaction protein for 7SK stability; PIP7S]
Gene, Accession #[LARP7], Gene ID: 51574, NCBI: NP_001253968.1, UniProt: Q4G0J3
Catalog #MBS9603436
Price$240, $280
Order / More InfoLARP7 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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