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Antigenic Specificity | Phospho-STAT5a (S726) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human (predicted reactivity: bovine, porcine) |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.39 |
Applications | Dot Blot (DB), ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This STAT5a Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S726 of human STAT5a. STAT5a is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated by, and mediates the responses of many cell ligands, such as IL2, IL3, IL7 GM-CSF, erythropoietin, thrombopoietin, and different growth hormones. Activation of this protein in myeloma and lymphoma associated with a TEL/JAK2 gene fusion is independe |
Immunogen | n/a |
Other Names | [Signal transducer and activator of transcription 5A; STAT5A; STAT5] |
Gene, Accession # | [STAT5A], Gene ID: 6776, NCBI: NP_003143.2, UniProt: P42229 |
Catalog # | MBS9207155 |
Price | $165, $370 |
Order / More Info | Phospho-STAT5a (S726) Antibody from MYBIOSOURCE INC. |
Product Specific References | Martens, N., et al., J. Biol. Chem. 280(14):13817-13823 (2005). Defilippi, P., et al., J. Cell Biol. 168(7):1099-1108 (2005). Sekine, Y., et al., J. Biol. Chem. 280(9):8188-8196 (2005). Sultan, A.S., et al., Oncogene 24(5):746-760 (2005). Moriggl, R., et al., Cancer Cell 7(1):87-99 (2005). |