Phospho-AKT1-T308 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityPhospho-AKT1-T308
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse
Isotypen/a
Formataffinity purified
Size0.1 mL
Concentrationn/a
ApplicationsWestern Blot (WB), Immunofluorescence (IF)
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DescriptionAKT1 is one of 3 closely related serine/threonine-protein kinases (AKT1, AKT2 and AKT3) called the AKT kinase, and which regulate many processes including metabolism, proliferation, cell survival, growth and angiogenesis. This is mediated through serine and/or threonine phosphorylation of a range of downstream substrates. Over 100 substrate candidates have been reported so far, but for most of them, no isoform specificity has been reported. AKT is responsible of the regulation of glucose uptake by mediating insulin-induced translocation of the SLC2A4/GLUT4 glucose transporter to the cell surface. Phosphorylation of PTPN1 at 'Ser-50' negatively modulates its phosphatase activity preventing dephosphorylation of the insulin receptor and the at
ImmunogenImmunogen: A synthetic phosphorylated peptide around T308 of human AKT1 (NP 005154.2).
Other Names[AKT; PKB; RAC; CWS6; PRKBA; PKB-ALPHA; RAC-ALPHA]
Gene, Accession #[AKT1], Gene ID: 207, NCBI: NP_001014431.1, UniProt: P31749
Catalog #MBS8550620
Price$280
Order / More InfoPhospho-AKT1-T308 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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