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Antigenic Specificity | DJ1/Park |
Clone | monoclonal |
Host Species | Mouse |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | DJ-1, also known as Park7, is a cytoplasmic protein that belongs to the ThiJ/Pfp1/DJ1 superfamily that functions as protein chaperones, catalases, proteases and kinases. DJ-1 was originally cloned as an oncogene that cooperatively transforms cells together with H-ras. Mutations in the DJ-1 gene are associated with rare forms of autosomal recessive early-onset Parkinson's disease. DJ-1 may also function as a redox-sensitive chaperone, as a sensor for oxidative stress, and it apparently protects neurons against oxidative stress and cell death. Augmenting DJ-1 activity might provide novel approaches to treating chronic neurodegenerative illnesses such as Parkinson's disease and acute damage such as stroke |
Immunogen | n/a |
Other Names | [DJ1/Park7], [dj1] |
Gene, Accession # | [DJ1/Park], NCBI: ACZ52888.1 |
Catalog # | MBS555673 |
Price | $405 |
Order / More Info | DJ1/Park Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |