Trk C Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityTrk C
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, ratpredicted: porcine, bovine, horse, chicken
Isotypen/a
Formatpeptide affinity purified
Size0.05 mL, 0.1 mL, 0.2 mL
Concentration1mg/ml
ApplicationsWestern Blot (WB), Peptide ELISA (EIA)
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DescriptionSpecificity: Trk C Antibody detects endogenous levels of Trk C. Description: Receptor tyrosine kinase involved in nervous system and probably heart development. Upon binding of its ligand NTF3/neurotrophin-3, NTRK3 autophosphorylates and activates different signaling pathways, including the phosphatidylinositol 3-kinase/AKT and the MAPK pathways, that control cell survival and differentiation.Post Translational Modifications: Ligand-mediated auto-phosphorylation.Subunit Structure: Exists in a dynamic equilibrium between monomeric (low affinity) and dimeric (high affinity) structures (By similarity). Binds SH2B2. Interacts with SQSTM1 and KIDINS220 (By similarity). Interacts with PTPRS (PubMed:25385546).Similarity: Be
ImmunogenImmunogen: A synthesized peptide derived from human Trk C. Tissue Specificity: Widely expressed but mainly in nervous tissue. Isoform 2 is expressed at higher levels in adult brain than in fetal brain.
Other Names[EC 2.7.10.1; ETS related protein neurotrophic receptor tyrosine kinase fusion; ETS related protein neurotrophic receptor tyrosine kinase fusion protein; ETV6 NTRK3 fusion; GP145 TrkC; gp145(trkC); GP145-TrkC; GP145TrkC; Neurotrophic tyrosine kinase receptor type 3; Neurotrophin 3 receptor; NT 3 growth factor receptor; NT 3 growth factor receptor precursor; NT 3 receptor; NT-3 growth factor receptor; Ntrk3; NTRK3_HUMAN; OTTHUMP00000192915; TRK C; Trk-C; TRKC; TrkC tyrosine kinase; Tyrosine kinase receptor C]
Gene, Accession #[Trk C], Gene ID: 4916, NCBI: NP_001012338.1, UniProt: Q16288
Catalog #MBS9611193
Price$225, $280, $340
Order / More InfoTrk C Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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