TOK-1 alpha Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityTOK-1 alpha
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatantigen affinity purified
Size0.1 mL
Concentrationn/a
ApplicationsWestern Blot (WB), Immunofluorescence (IF)
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DescriptionThis gene product was isolated on the basis of its interaction with BRCA2 and p21 proteins. It is an evolutionarily conserved nuclear protein with multiple interacting domains. The N-terminal half shares moderate homology with regions of calmodulin and M-calpain, suggesting that it may also bind calcium. Functional studies indicate that this protein may be an important cofactor for BRCA2 in tumor suppression, and a modulator of CDK2 kinase activity via p21. This protein has also been implicated in the regulation of BRCA2 and RAD51 nuclear focus formation, double-strand break-induced homologous recombination, and cell cycle progression. Multiple transcript variants encoding different isoforms have been described for this gene. [provided by R
ImmunogenImmunogen Type: Peptide Immunogen Description: Synthetic peptide contain a sequence corresponding to a region within amino acids 181 and 233 (Q9P287) of BCCIP
Other Names[BRCA2 and CDKN1A-interacting protein isoform BCCIPalpha; BRCA2 and CDKN1A-interacting protein; BRCA2 and CDKN1A-interacting protein; BRCA2 and CDKN1A interacting protein; P21- and CDK-associated protein 1; Protein TOK-1]
Gene, Accession #[TOK-1 alpha], Gene ID: 56647, NCBI: NP_057651
Catalog #MBS9401839
Price$320
Order / More InfoTOK-1 alpha Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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