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Antigenic Specificity | CD152, Blocking (CTLA4, Cytolytic T-lymphocyte-associated Antigen 4) |
Clone | [5D3] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1,k |
Format | Protein A purified |
Size | 0.05 mg, 0.1 mg |
Concentration | 1 mg/mL |
Applications | Suitable for use in Flow Cytometry, ELISA and Immunohistochemistry. Other applications not tested |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Recognizes CTLA-4 expressed on activated T cells. Blocks binding of CD152 Human, IgG2a Mouse Fc, Fusion Protein to its CD80/CD86receptor. Human CD152 (CTLA-4) is a cell surface glycoprotein expressed at low levels on activated T-cells. CD152 is a highaffinity receptor for the costimulatory molecules CD80 (B7-1) and CD86 (B7-2) and appears to function as a negative regulator of T cell activation. |
Immunogen | Immunogen: Stimulated human PBL's and human CD152 Ig fusion protein. |
Other Names | n/a |
Gene, Accession # | n/a |
Catalog # | MBS632798 |
Price | $415, $550 |
Order / More Info | CD152, Blocking (CTLA4, Cytolytic T-lymphocyte-associated Antigen 4) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |