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Antigenic Specificity | GABA Transporter 1/GAT 1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Description: Rabbit IgG polyclonal antibody for Sodium- and chloride-dependent GABA transporter 1(SLC6A1) detection. Tested with WB, IHC-P in Human, Mouse, Rat. Background: SLC6A1(Solute Carrier family 6(Neurotransmitter transporter, Gaba), Member 1), also called GABATR or GABATHG, encodes a gamma-aminobutyric acid(GABA) transporter, which removes GABA from the synaptic cleft. The SLC6A1 gene contains 15 exons and is approximately 25 kb by Lam et al. And it is mapped on 3p25.3. Zomot et al.(2007) showed that introduction of a negatively charged amino acid at or near 1 of the 2 putative sodium binding sites of the GABA transporter GAT1 from rat brain(also calledSLC6A1) renders both net flux and exchange of GABA largely chloride independent. |
Immunogen | Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human GABA Transporter 1 (473-487aa WFYGVNRFYDNIQEM), identical to the related rat and mouse sequences. |
Other Names | [Sodium- and chloride-dependent GABA transporter 1(GAT-1); solute carrier family 6(neurotransmitter transporter, GABA), member 1; GABATHG; GABATR; GABT 1; GABT1; GAT-1; GAT1; SC6A1_HUMAN; SLC6A1; Sodium and chloride dependent GABA transporter 1; Sodium- and chloride-dependent GABA transporter 1; Solute carrier family 6(neurotransmitter transporter GABA) member 1; Solute carrier family 6 member 1], [SLC6A1; SLC6A1; GAT1; GABATR; GABATHG; GABATR; GABT1; GAT1; GAT-1] |
Gene, Accession # | [SLC6A1], Gene ID: 6529, NCBI: P30531.2, UniProt: P30531 |
Catalog # | MBS175748 |
Price | $315 |
Order / More Info | GABA Transporter 1/GAT 1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |