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Antigenic Specificity | Mouse IL18BP |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | n/a |
Isotype | n/a |
Format | purified |
Size | 0.1 mg, 0.2 mg |
Concentration | n/a |
Applications | ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | IL-18BP is a secreted protein that binds IL-18 with high affinity and prevents its interaction with the IL-18R. Different isoforms of IL-18BP have been demonstrated, four in human and two in the murine system, and biological activity is limited to particular isoforms.IL-18 binding protein (IL-18BP) is a constitutively expressed and secreted protein that resembles the extracellular domains of Ig-like receptors but has no transmembrane form.Because IL-18 is one of the early signals leading to IFN-gamma production by T- helper (Th) type-1 cells, blocking IL-18 activity by IL-18BP may be involved in down-modulation of the early phases of immune responses. |
Immunogen | n/a |
Other Names | [Rabbit mouse IL18BP purified; il-18; il18; il18bp;; PAb], [IL-18] |
Gene, Accession # | [IL18BP], Gene ID: 10068, NCBI: NP_001034748.1, UniProt: O95998 |
Catalog # | MBS551055 |
Price | $375, $495 |
Order / More Info | Mouse IL18BP Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |