TNF-alpha Antibody from MYBIOSOURCE INC.
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| Edit | |
|---|---|
| Antigenic Specificity | TNF-alpha |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse |
| Isotype | n/a |
| Format | affinity purified |
| Size | 0.05 mL, 0.1 mL, 0.2 mL |
| Concentration | 1mg/ml |
| Applications | Western Blot (WB), Immunoprecipitation (IP) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | TNF-alpha, the prototypical member of the TNF protein superfamily, is a homotrimeric type-II membrane protein (1,2). Membrane-bound TNF-alpha is cleaved by the metalloprotease TACE/ADAM17 to generate a soluble homotrimer (2). Both membrane and soluble forms of TNF-alpha are biologically active. TNF-alpha is produced by a variety of immune cells including T cells, B cells, NK cells, and macrophages (1). Cellular response to TNF-alpha is mediated through interaction with receptors TNF-R1 and TNF-R2 and results in activation of pathways that favor both cell survival and apoptosis depending on the cell type and biological context. Activation of kinase pathways (including JNK, Erk (p44/42), p38 MAPK, and NF-kappaB) promotes the survival of cells |
| Immunogen | Immunogen: A synthetic peptide of human TNF-alpha Calculated Molecular Weight: 26kDa |
| Other Names | [TNF-a; TNF; TNFSF2; DIF; Tumor necrosis factor; TNF a; TNF alpha], [TNF; TNF; DIF; TNFA; TNFSF2; TNF-alpha; TNFA; TNFSF2; TNF-a; NTF; ICD1; ICD2] |
| Gene, Accession # | [TNF], Gene ID: 7124, NCBI: P01375.1, UniProt: P01375 |
| Catalog # | MBS127568 |
| Price | $275, $430, $655 |
| Order / More Info | TNF-alpha Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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