SOD1 (UbetaB) Antibody from MYBIOSOURCE INC.
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|---|---|
| Antigenic Specificity | SOD1 (UbetaB) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | alkaline phosphatase (AP) conjugate |
| Size | 0.1 mg |
| Concentration | 1mg/ml |
| Applications | Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Background Info: Recognizes a conformation specific epitope where the beta barrel is unfolded Scientific Background: Superoxide dismutase (SOD) is an endogenously produced intracellular enzyme present in almost every cell in the body (2). It works by catalyzing the dismutation of the superoxide radical O2 to O2 and H2O2, which are then metabolized to H2O and O2 by catalase and glutathione peroxidase (1,4). In general, SODs play a major role in antioxidant defense mechanisms (3). There are two main types of SOD in mammalian cells. One form (SOD1) contains Cu and Zn ions as a homodimer and exists in the cytoplasm. The two subunits of 16 kDa each are linked by two cysteines forming an intra-subunit disulphide bridge (2). Misfolding of SOD1 ha |
| Immunogen | n/a |
| Other Names | [Superoxide dismutase 1; SOD; SOD1 unfolded beta barrel region], [SOD1; SOD1; ALS; SOD; ALS1; IPOA; hSod1; HEL-S-44; homodimer; hSod1] |
| Gene, Accession # | Gene ID: 6647, NCBI: CAG46542, UniProt: P00441 |
| Catalog # | MBS805206 |
| Price | $410 |
| Order / More Info | SOD1 (UbetaB) Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Barrister J.V., et al. (1987). Crit. Rev. Biochem. 22:111-180. 2. Furukawa Y., and O'Halloran T. (2006) Antioxid Redox Signal. 8(5-6):847-67. 3. Gao B., et al. (2003) Am J Physiol Lung Cell Mol Physiol. 284:L917-L925. 4. Hassan H.M. (1988) Free Radical Biol. Med. 5:377-385. 5. Kerman A., et al. (2010) Acta Neuropathol. 119:335-344. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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