HAX1 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | HAX1 |
| Clone | [AT3C5] |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG2b, k |
| Format | Protein G purified |
| Size | 0.05 mL, 0.1 mL |
| Concentration | 1mg/ml |
| Applications | ELISA (EIA), Western Blot (WB), Immunocytochemistry (ICC), Immunofluorescence (IF), Flow Cytometry (FC/FACS) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | HAX1 is known to associate with hematopoietic cell-specific Lyn substrate 1 (HS1), one of the substrates of receptor-coupled tyrosine kinases activated during clonal expansion and deletion in lymphoid cells. It also interacts with the product of the polycystic kidney disease 2 (PKD2) gene and with the F-actin-binding protein, cortactin. HAX1 is also reported to bind to hairpin structures in vimentin and DNA polymerase beta mRNAs, so may play a role in mRNA stability and transport. It may also function in promoting cell survival. Defects in HAX1 are the cause of autosomal recessive severe congenital neutropenia 3 (SCN3) also called Kostmann disease. |
| Immunogen | Immunogen: Recombinant human HAX1 (1-279aa) purified from E. coli |
| Other Names | [HCLS1 associated protein X-1; HS1BP1; HCLSBP1; HCLS1 (and PKD2) associated protein], [HAX1; HAX1; SCN3; HS1BP1; HCLSBP1; HS1BP1; HAX-1; HSP1BP-1] |
| Gene, Accession # | [HAX1], Gene ID: 10456, NCBI: NP_006109, UniProt: O00165 |
| Catalog # | MBS200151 |
| Price | $240, $315 |
| Order / More Info | HAX1 Antibody from MYBIOSOURCE INC. |
| Product Specific References | Klein C, et al., (2007) Nat Genet. 39 (1):86-92; Yin H, et al., (2001) Cytokine. 15 (3):122-37 |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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