Edit |   |
---|---|
Antigenic Specificity | Androgen Receptor |
Clone | [SPM335] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 kappa |
Format | purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC), ELISA, Immunoprecipitation (IP), Flow Cytometry (FC), |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This antibody recognizes human Androgen Receptor protein. The other species was not tested. The androgen receptor belongs to the nuclear receptor subfamily 3 group C member 4 which is encoded by the Ar (alsoknown as Andr, Nr3c4, Tfm) gene. Androgen receptor (AR) is a hormone-activated transcription regulator that playsimportant roles in normal prostate development and function, as well as in malignant prostate transformation. The binding ofan androgenic hormone (testosterone or dihydrotestosterone) induces a conformational change in AR, resulting itsdissociation from heat shock proteins and subsequent translocation from the cytosol to nucleus, where it dimerizes andmediates either transcription activation or repression in a target gene |
Immunogen | Antigen Preparation: A synthetic peptide sequence comprising amino acids 301-321 of human androgen receptor. |
Other Names | n/a |
Gene, Accession # | [AR], NCBI: AAD14959.1 |
Catalog # | MBS460253 |
Price | $285 |
Order / More Info | Androgen Receptor Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |