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Antigenic Specificity | TORC1 |
Clone | [4E7-C1-F9-E6] |
Host Species | Mouse |
Reactive Species | human, mouse, monkey, rat |
Isotype | IgM |
Format | unconjugated |
Size | 0.05 mL, 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunocytochemistry (ICC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This antibody detects endogenous levels of CRTC1 and does not cross-react with related proteins. Transcriptional coactivator for CREB1 which activates transcription through both consensus and variant cAMP response element (CRE) sites.Acts as a coactivator, in the SIK/TORC signaling pathway,being active when dephosphorylated and acts independently of CREB1 'Ser-133' phosphorylation.Enhances the interaction of CREB1 with TAF4.Regulates the expression of specific CREB-activated genes such as the steroidogenic gene,StAR.Potent coactivator of PGC1alpha and inducer of mitochondrial biogenesis in muscle cells.Also coactivator for TAX activation of the human T-cell leukemia virus type 1 (HTLV-1) long terminal repeats (LTR).In the hippocampus, invol |
Immunogen | Immunogen Type: Recombinant Protein Immunogen Description: Purified recombinant human CRTC1 protein fragments expressed in E Coli. |
Other Names | [KIAA0616; CREB regulated transcription coactivator 1; CREB-regulated transcription coactivator 1; CRTC1; CRTC1_HUMAN; FLJ14027; KIAA0616; MECT 1; Mucoepidermoid carcinoma translocated 1; Mucoepidermoid carcinoma translocated protein 1; TORC-1; TORC1] |
Gene, Accession # | [TORC1], Gene ID: 23373, NCBI: NP_001091952.1, UniProt: Q6UUV9 |
Catalog # | MBS9400391 |
Price | $200, $255 |
Order / More Info | TORC1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |