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Antigenic Specificity | Complement, C1q, Human |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | serum |
Size | 1 mL |
Concentration | n/a |
Applications | ELISA (EL/EIA), Radioimmunoassay (RIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Recognizes human C1Q: 100%. C1q is serum glycoprotein of 18-polypeptides chains consisting of three non-identical subunits, A (29kD), B (26kD) and C (246aa, 19kD) in molar ratio of 1:2:2. C1Q in the plasma is complexed with two proenzymes C1r and two C1s molecules to form the first component of complement (C1). Activation of complement via classical pathway is triggered by binding of globular head of C1q to immune complexes containing IgG (Fc-region) or IgM or to a variety of other activating substances, including C-reactive protein, retrovirus and mitochondria. Subsequent to C1q binding, c1r and C1s are converted to proteolytic enzymes that are responsible to continuation of activation via the classical pathway. Normal plasma concentration |
Immunogen | Immunogen: Human C1Q |
Other Names | [-Complement, C1q, Human], [C1QC; C1QC; C1QG; C1Q-C; C1QG] |
Gene, Accession # | Gene ID: 714, NCBI: NP_001107573.1, UniProt: P02747 |
Catalog # | MBS627016 |
Price | $420 |
Order / More Info | Complement, C1q, Human Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |