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Antigenic Specificity | RPE65 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peroxidase (HRP) conjugate |
Size | 0.05 mg, 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Plays important roles in the production of 11-cis retinal and in visual pigment regeneration. The soluble form binds vitamin A (all-trans-retinol), making it available for LRAT processing to all-trans-retinyl ester. The membrane form, palmitoylated by LRAT, binds all-trans-retinyl esters, making them available for IMH (isomerohydrolase) processing to all-cis-retinol. The soluble form is regenerated by transferring its palmitoyl groups onto 11-cis-retinol, a reaction catalyzed by LRAT. The enzymatic activity is linearly dependent of the expression levels and membrane association. |
Immunogen | Immunogen: Recombinant Human Retinoid isomerohydrolase protein (348-484AA) Research Area: Tags & Cell Markers |
Other Names | [Retinoid isomerohydrolase; All-trans-retinyl-palmitate hydrolase; Retinal pigment epithelium-specific 65 kDa protein; Retinol isomerase; RPE65] |
Gene, Accession # | [RPE65], Gene ID: 6121, NCBI: NP_000320.1, UniProt: Q16518 |
Catalog # | MBS7108288 |
Price | $160, $235 |
Order / More Info | RPE65 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |