Edit |   |
Antigenic Specificity | TNC |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: TNC antibody detects endogenous levels of total TNC. Function: Extracellular matrix protein implicated in guidance of migrating neurons as well as axons during development, synaptic plasticity as well as neuronal regeneration. Promotes neurite outgrowth from cortical neurons grown on a monolayer of astrocytes. Ligand for integrins alpha-8/beta-1, alpha-9/beta-1, alpha-V/beta-3 and alpha-V/beta-6. In tumors, stimulates angiogenesis by elongation, migration and sprouting of endothelial cells (PubMed:19884327).Subunit Structure: Homohexamer; disulfide-linked. A homotrimer may be formed in the triple coiled-coil region and may be stabilized by disulfide rings at both ends. Two of such half-hexabrachions may be disulfide linked |
Immunogen | Immunogen: A synthesized peptide derived from human TNC Subcellular Location: Secreted > Extracellular Space > Extracellular Matrix. Tissue Specificity: By TGFB1. Predicted Cross Reactivity: Pig, Bovine, Horse, Sheep, Rabbit, Dog, Chicken Similarity: Pig (89%), Bovine (89%), Horse (100%), Sheep (89%), Rabbit (100%), Dog (100%), Chicken (100%) |
Other Names | [150 225; Cytotactin; Glioma associated extracellular matrix antigen; Glioma-associated-extracellular matrix antigen; GMEM; GP 150 225; GP 150-225; GP; Hexabrachion; HXB; JI; MGC167029; Miotendinous antigen; Myotendinous antigen; Neuronectin; TENA_HUMAN; Tenascin; Tenascin-C; Tenascin-C isoform 14/AD1/16; TenascinC; TN; TN C; TN-C; TNC] |
Gene, Accession # | [TNC], Gene ID: 3371, NCBI: NP_002151.2, UniProt: P24821 |
Catalog # | MBS9608520 |
Price | $240, $280 |
Order / More Info | TNC Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |