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Antigenic Specificity | Chapsyn-110 |
Clone | [S18-30] |
Host Species | Mouse |
Reactive Species | human, mouse, rat |
Isotype | IgG1 |
Format | APC-Cy7 conjugate |
Size | 0.1 mg |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunocytochemistry (ICC), Immunofluorescence (IF), Antibody Microarray (AM) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Detects ~110 kDa. No cross-reactivity against other MAGUK family members, PSD95, SAP97, SAP102, expressed in transfected cells. Weak human detection. Chapsyn-110, is a part of the membrane-associated putative guanylate kinase (MAGUK) family. It binds directly to the NMDA receptor, and Shaker K+ channel subunits, and is 70-80% identical to PSD-95/SAP90 and SAP97 (1). It associated tightly with the postsynaptic density I brain, and mediates the clustering of both NMDA recpetors and K+ channels in heterologous cells. The encoded protein forms a heterodimer with PSD-95 that may interact at postsynaptic sites to form a multimeric scaffold for the clustering of receptors, ion channels, and associated signaling proteins (1, 2). |
Immunogen | Immunogen: Fusion protein amino acids 1-852 of rat Chapsyn-110 |
Other Names | [Mouse Rat Chapsyn-110 IgG1; Chapsyn-110 : APC/Cy7; PSD93; Chapsyn-110; MGC131811; PSD-93; Discs Large Homolog 2; DLG2; Postsynaptic density protein PSD-93; DLGH2; Channel-associated protein of synapse-110] |
Gene, Accession # | Gene ID: 64053, NCBI: NP_071618.1, UniProt: Q63622 |
Catalog # | MBS8002896 |
Price | $510 |
Order / More Info | Chapsyn-110 Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Kim E., et al. (1996) Neuron. 17:103-113. 2. Godreau D., Neyroud N., Vranckx R. and Hatem S. (2004) Med Sci (Paris). 20(1): 84-88. |