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Antigenic Specificity | Human CD11b |
Clone | [4ALM2; 1.6.11] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | unconjugated |
Size | 50 tests, 100 tests, 500 tests |
Concentration | n/a |
Applications | Flow Cytometry (FC/FACS), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | 4ALM2/1.6.11 reacts with CD11b, a member of the integrin a chain family with 165 kDa MW. which is expressed on NK cells, monocytes, granulocytes and subsets of T and B cells. It associates with CD18 to form CD11b/CD18 complex.The cellular function of CD11b is on neutrophil and monocyte interactions with stimulated endothelium; Phagocytosis of iC3b or IgG coated particles as a receptor; Chemotaxis and apoptosis.* CD11b is absent in Leukocyte Adhesion Deficiency (LAD-1) patients who have major problems with bacterial infections.This clone is cross reactive with non-human primate. |
Immunogen | n/a |
Other Names | [CD11b, partial; CD11b; integrin alpha-M; CD11b] |
Gene, Accession # | [CD11b], Gene ID: 397459, NCBI: AAB16869.1 |
Catalog # | MBS8500642 |
Price | $215, $280, $350 |
Order / More Info | Human CD11b Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Ling NR et al., eds. (1987) Leucocyte Typing III: White Cell Differentiation Antigens, Oxford University Press, New York. 303-334 2. Petty HR nd Todd RF. (1996) Immunol. Today 17:209 3. Springer TA (1994) Cell 76:301 4. Stewart M et al (1995) Curr Opin Cell Biol 7:690. |