XIAP Antibody from MYBIOSOURCE INC.
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|---|---|
| Antigenic Specificity | XIAP |
| Clone | monoclonal |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG1, kappa |
| Format | Protein A purified |
| Size | 0.1 mL |
| Concentration | n/a |
| Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Multi-functional protein which regulates not only caspases and apoptosis, but also modulates inflammatory signaling and immunity, copper homeostasis, mitogenic kinase signaling, cell proliferation, as well as cell invasion and metastasis. Acts as a direct caspase inhibitor. Directly bind to the active site pocket of CASP3 and CASP7 and obstructs substrate entry. Inactivates CASP9 by keeping it in a monomeric, inactive state. Acts as an E3 ubiquitin-protein ligase regulating NF-kappa-B signaling and the target proteins for its E3 ubiquitin-protein ligase activity include: RIPK1, CASP3, CASP7, CASP8, CASP9, MAP3K2/MEKK2, DIABLO/SMAC, AIFM1, CCS and BIRC5/survivin. Ubiquitinion of CCS leads to enhancement of its chaperone activity toward its p |
| Immunogen | Immunogen: This XIAP antibody is generated from a mouse immunized with a recombinant protein human XIAP. |
| Other Names | [API3; ILP1; MIHA; XLP2; BIRC4; IAP-3; hIAP3; hIAP-3] |
| Gene, Accession # | [XIAP], Gene ID: 331, NCBI: NP_001158.2, UniProt: P98170 |
| Catalog # | MBS8559081 |
| Price | $280 |
| Order / More Info | XIAP Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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