Human Interleukin-6 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Human Interleukin-6 |
| Clone | [SB9H6] |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG1 |
| Format | Protein A purified |
| Size | 0.5 mg, 1 mg |
| Concentration | n/a |
| Applications | n/a |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | IL6 is produced by many different cell types. The main sources in vivo are stimulated monocytes, fibroblasts, and endothelial cells. Macrophages, T-cells and B-lymphocytes, granulocytes, smooth muscle cells, eosinophils, chondrocytes, osteoblasts, mast cells, glial cells, and keratinocytes also produce IL6 after stimulation. IL6 is a member of a family of cytokines, which also includes LIF, CNTF, Oncostatin M, IL11, and CT- 1. All known members of the IL6 cytokine family induce hepatic expression of acute phase proteins. The IL6 receptor is expressed on T-cells, mitogen-activated B-cells, peripheral monocytes and some macrophage- and B-cell derived tumor cell types. It is not expressed in resting B-cells but in resting T- cells. The IL6 rec |
| Immunogen | Host Note: This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with recombinant E. coli-derived Human IL-6. |
| Other Names | [il-6; il6; interleukin-6; B-cell stimulatory factor; bsf;; mab], [IL6; IFNB2; IL-6; BSF-2; CDF; IFN-beta-2] |
| Gene, Accession # | [IL-6], Gene ID: 3569, NCBI: AAC41704, UniProt: P05231 |
| Catalog # | MBS550031 |
| Price | $550, $855 |
| Order / More Info | Human Interleukin-6 Antibody from MYBIOSOURCE INC. |
| Product Specific References | • IL-6 protects against hyperoxia-induced mitochondrial damage via bcl-2-induced bak interactions with mitofusions.Am. J. Respir. Cell Mol. Biol., Oct 2009; 41: 385 - 396. • long-term safety and efficacy of tocilizumab, an anti-IL-6 receptor monoclonal antibody, in monotherapy, in patients with rheumatoid arthritis (the stream study) : evidence of safety and efficacy in a 5-year extension study.Ann Rheum Dis, Oct 2009; 68: 1580 - 1584. • the second bovine β-galactoside-2,6-sialyltransferase (st6gal ii) : genomic organization and stimulation of its in vitro expression by IL-6 in bovine mammary epithelial cells.Glycobiology, Oct 2009; 19: 1082 - 1093. • IL-6 -174g/c promoter polymorphism in acute appendicitis.Lab Med, Oct 2009; 40: 600 - 603. • cell surface-bound il-1 is an upstream regulator of the senescence-associated IL-6/il-8 cytokine network.PNAS, Sep 2009; 10.1073/pnas.0905299106. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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