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Antigenic Specificity | HP1-alpha |
Clone | [3G2-H10-A6] |
Host Species | Mouse |
Reactive Species | human, mouse |
Isotype | IgG2b |
Format | affinity purified |
Size | 0.1 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunocytochemistry (ICC), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Entrez Summary: This gene encodes a highly conserved nonhistone protein, which is a member of the heterochromatin protein family. The protein is enriched in the heterochromatin and associated with centromeres. The protein has a single N-terminal chromodomain which can bind to histone proteins via methylated lysine residues, and a C-terminal chromo shadow-domain (CSD) which is responsible for the homodimerization and interaction with a number of chromatin-associated nonhistone proteins. The encoded product is involved in the formation of functional kinetochore through interaction with essential kinetochore proteins. The gene has a pseudogene located on chromosome 3. Multiple alternatively spliced variants, encoding the same protein, have bee |
Immunogen | Immunogen: Purified recombinant human HP1 alpha protein fragments expressed in E Coli. Sensitivity: This antibody detects endogenous levels of HP1 alpha and does not cross-react with related proteins. Sequence Similarities: Contains 2 chromo domains |
Other Names | [Antigen p25; Cbx 5; Cbx5; CBX5_HUMAN; CG8409; Chromobox homolog 5 (Drosophila HP1 alpha); Chromobox homolog 5 (HP1 alpha homolog Drosophila); Chromobox homolog 5 (HP1 alpha homolog, Drosophila); Chromobox homolog 5; Chromobox protein homolog 5; Chromobox protein homologue 5; Heterochromatin protein 1 alpha; Heterochromatin protein 1; Heterochromatin protein 1 homolog alpha; HP 1; HP 1A; HP1 alpha; HP1 alpha homolog; HP1; HP1A; HP1Hs alpha; Su (var)205], [cbx5; HP1; HP1A] |
Gene, Accession # | [HP1-alpha], Gene ID: 23468, NCBI: NP_001120793.1, UniProt: P45973 |
Catalog # | MBS475136 |
Price | $335 |
Order / More Info | HP1-alpha Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |