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Antigenic Specificity | Human DNAJC2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | n/a |
Applications | ELISA (EIA), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Acts both as a chaperone in the cytosol and as a chromatin regulator in the nucleus. When cytosolic, acts as a molecular chaperone: component of the ribosome-associated complex (RAC), a complex involved in folding or maintaining nascent polypeptides in a folding-competent state. In the RAC complex, stimulates the ATPase activity of the ribosome-associated pool of Hsp70-type chaperones HSPA14 that bind to the nascent polypeptide chain. When nuclear, mediates the switching from polycomb-repressed genes to an active state: specifically recruited at histone H2A ubiquitinated at 'Lys-119' (H2AK119ub), and promotes the displacement of the polycomb PRC1 complex from chromatin, thereby facilitating transcription activation. Specifically binds DNA s |
Immunogen | Immunogen: Recombinant human DnaJ homolog subfamily C member 2 protein (1-140aa) Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-79397 |
Other Names | [M-phase phosphoprotein 11; Zuotin-related factor 1; DNAJC2; MPHOSPH11; MPP11; ZRF1], [DNAJC2; DNAJC2; ZRF1; ZUO1; MPP11; MPHOSPH11; MPHOSPH11; MPP11; ZRF1] |
Gene, Accession # | [DNAJC2], Gene ID: 27000, NCBI: NP_001123359.1, UniProt: Q99543 |
Catalog # | MBS1492997 |
Price | $120, $160 |
Order / More Info | Human DNAJC2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |