Human DNAJC2 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityHuman DNAJC2
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatantigen affinity purified
Size0.05 mL, 0.1 mL
Concentrationn/a
ApplicationsELISA (EIA), Immunohistochemistry (IHC)
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DescriptionActs both as a chaperone in the cytosol and as a chromatin regulator in the nucleus. When cytosolic, acts as a molecular chaperone: component of the ribosome-associated complex (RAC), a complex involved in folding or maintaining nascent polypeptides in a folding-competent state. In the RAC complex, stimulates the ATPase activity of the ribosome-associated pool of Hsp70-type chaperones HSPA14 that bind to the nascent polypeptide chain. When nuclear, mediates the switching from polycomb-repressed genes to an active state: specifically recruited at histone H2A ubiquitinated at 'Lys-119' (H2AK119ub), and promotes the displacement of the polycomb PRC1 complex from chromatin, thereby facilitating transcription activation. Specifically binds DNA s
ImmunogenImmunogen: Recombinant human DnaJ homolog subfamily C member 2 protein (1-140aa) Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-79397
Other Names[M-phase phosphoprotein 11; Zuotin-related factor 1; DNAJC2; MPHOSPH11; MPP11; ZRF1], [DNAJC2; DNAJC2; ZRF1; ZUO1; MPP11; MPHOSPH11; MPHOSPH11; MPP11; ZRF1]
Gene, Accession #[DNAJC2], Gene ID: 27000, NCBI: NP_001123359.1, UniProt: Q99543
Catalog #MBS1492997
Price$120, $160
Order / More InfoHuman DNAJC2 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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