ROCKII (Paired Thr249), Non-Phospho Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-ROCKII (Paired Thr249), Non-Phospho antibody, protein, ELISA kits.
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| Antigenic Specificity | ROCKII (Paired Thr249), Non-Phospho |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat, chicken, bovine, dog |
| Isotype | n/a |
| Format | epitope affinity purified |
| Size | 0.1 mg |
| Concentration | Size: 100 ug/200 ul |
| Applications | ELISA, Western Blot, Immunohistochemistry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This antibody recognizes ~165 kDa of human ROCKII without a phosphorylation site ofThr249. It does not react to phosphorylated protein. This antibody also reacts with mouse and rat. The other species are not tested. Rho A-dependent kinase (ROCKII), or ROK-alpha, is identified a serine/threonine kinase, a downstream effector of the small GTPase Rho, mediating effects of Rho on the actin cytoskeleton, formation of actin stress fibers and focal adhesions, ROCKII alters cardiac myofilament response to Ca2+ by mechanisms involving phosphorylation of thin filament proteins. ROCK-II induces a depression in maximum ATPase rate and tension, which is associated with phosphorylation of troponin T (TnT), troponin I (TnI), and myosin-binding protein C ( |
| Immunogen | Antigen Preparation: A synthetic peptide corresponding to the epitope -CDTAV- without a phosphorylation site Thr396 of human RockII protein. This sequence is identical among human, mouse, rat, chicken, dog and bovine. |
| Other Names | n/a |
| Gene, Accession # | [Rho Kinase/ROCKII (Paired T249)] |
| Catalog # | MBS462123 |
| Price | $285 |
| Order / More Info | ROCKII (Paired Thr249), Non-Phospho Antibody from MYBIOSOURCE INC. |
| Product Specific References | Susan Vahebi, et al, Functional Effects of Rho-Kinase-Dependent Phosphorylation of Specific Sites on Cardiac Troponin. Circulation Research. 2005;96:740-747. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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