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Antigenic Specificity | MAPK9 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | biotin conjugate |
Size | 0.05 mg, 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Serine/threonine-protein kinase involved in various processes such as cell proliferation, differentiation, migration, transformation and programmed cell death. Extracellular stimuli such as proinflammatory cytokines or physical stress stimulate the stress-activated protein kinase/c-Jun N-terminal kinase (SAP/JNK) signaling pathway. In this cascade, two dual specificity kinases MAP2K4/MKK4 and MAP2K7/MKK7 phosphorylate and activate MAPK9/JNK2. In turn, MAPK9/JNK2 phosphorylates a number of transcription factors, primarily components of AP-1 such as JUN and ATF2 and thus regulates AP-1 transcriptional activity. In response to oxidative or ribotoxic stresses, inhibits rRNA synthesis by phosphorylating and inactivating the RNA polymerase 1-spec |
Immunogen | Immunogen: Recombinant human Mitogen-activated protein kinase 9 protein(1-424AA) Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-46013 / sc-46011 / sc-827 / sc-572 |
Other Names | [Mitogen-activated protein kinase 9; MAP kinase 9; MAPK 9; Stress-activated protein kinase 1a; SAPK1a; Stress-activated protein kinase JNK2; c-Jun N-terminal kinase 2; MAPK9; JNK2; PRKM9; SAPK1A], [MAPK9; MAPK9; JNK2; SAPK; p54a; JNK2A; JNK2B; PRKM9; JNK-55; SAPK1a; JNK2BETA; p54aSAPK; JNK2ALPHA; JNK2; PRKM9; SAPK1A; MAP kinase 9; MAPK 9; SAPK1a] |
Gene, Accession # | [MAPK9], Gene ID: 5601, NCBI: NP_001128516.1, UniProt: P45984 |
Catalog # | MBS1495271 |
Price | $160, $235 |
Order / More Info | MAPK9 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |