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Antigenic Specificity | Trem1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | n/a |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin, Immunohistochemistry (IHC) Frozen |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Trem1 is encoded by the Trem1 gene. The expression of Trem1 is in monocytes and neutrophils but not in lymphocytes, dendritic cells, or other cell types. Trem1 is a 30-kD glycoprotein that is reduced to 26 kD by deglycosylation, in agreement with the predicted molecular mass. The Trem1 gene which contains 4 exons maps to chromosome 6p21.1, within a TREM gene cluster and the mouse Trem1 gene maps to chromosome 17 in a region that shows homology of synteny to human chromosome 6. The expression of Trem1 is upregulated by stimulation with lipopolysaccharide (LPS), gram-negative bacteria, and fungi. Cross-linking of Trem1 on neutrophils induces interleukin-8 (IL8) and myeloperoxidase secretion, while cross-linking on monocytes induces not only s |
Immunogen | Immunogen: Trem1 antibody was raised in Rabbit using a synthetic peptide corresponding to a sequence in the middle of Rabbit Trem1 as the immunogen |
Other Names | [Affinity Purified Rabbit Trem1; Trem1; Trem1; Trem-1; Triggering receptor expressed on myeloid cells 1; Trem 1; Trem1; Trem-1; Trem 1] |
Gene, Accession # | [Trem1], Gene ID: 54210, UniProt: Q9NP99 |
Catalog # | MBS5312891 |
Price | $515 |
Order / More Info | Trem1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |