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Antigenic Specificity | ESR2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Nuclear hormone receptor. Binds estrogens with an affinity similar to that of ESR1, and activates expression of reporter genes containing estrogen response elements (ERE) in an estrogen-dependent manner (PubMed:20074560). Isoform beta-cx lacks ligand binding ability and has no or only very low ere binding activity resulting in the loss of ligand-dependent transactivation ability. DNA-binding by ESR1 and ESR2 is rapidly lost at 37 degrees Celsius in the absence of ligand while in the presence of 17 beta-estradiol and 4-hydroxy-tamoxifen loss in DNA-binding at elevated temperature is more gradual. |
Immunogen | Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human ESR2 (NP 001201832.1). |
Other Names | [Erb; ESRB; ESTRB; NR3A2; ER-BETA; ESR-BETA] |
Gene, Accession # | [ESR2], Gene ID: 2100, NCBI: NP_001035365.1, UniProt: Q92731 |
Catalog # | MBS8544978 |
Price | $280 |
Order / More Info | ESR2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |