ACY1 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityACY1
Clone[AT1E2]
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG2b,k
FormatProtein A purified
Size0.05 mL, 0.1 mL
Concentration1mg/ml
ApplicationsELISA (EIA), Western Blot (WB), Flow Cytometry (FC/FACS), Immunocytochemistry (ICC), Immunofluorescence (IF)
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DescriptionAminoacylase-1, also designated N-acyl-L-amino-acid amidohydrolase or ACY1, is a member of the largest metallopeptidase family called M20A. Aminoacylase-1 is a zinc-binding homodimeric enzyme expressed in kidney, brain, placenta and spleen. It is the most abundant of the aminoacylases. Defects in ACY1 are the cause of aminoacylase-1 deficiency (ACY1D). ACY1D results in a metabolic disorder manifesting with encephalopathy, unspecific psychomotor delay, psychomotor delay with atrophy of the vermis and syringomyelia, marked muscular hypotonia or normal clinical features. All affected individuals exhibit markedly increased urinary excretion of several N-acetylated amino acids.
ImmunogenImmunogen: Recombinant human ACY1 (1-408aa) purified from E. coli
Other Names[Aminoacylase 1; ACY1D; ACYLASE; Aminoacylase 1], [ACY1; ACY1; ACY-1; ACY1D; HEL-S-5; ACY-1]
Gene, Accession #[ACY1], Gene ID: 95, NCBI: NP_000657, UniProt: Q03154
Catalog #MBS200303
Price$240, $315
Order / More InfoACY1 Antibody from MYBIOSOURCE INC.
Product Specific ReferencesCook R.M., et al. (1993) J Biol Chem 268 (23): 17010-17017; Lindner H.A., et al. (2003) J Biol Chem 278 (45): 44496-44504
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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