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Antigenic Specificity | CE164 (N-term), 246-274 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.5 |
Applications | Western Blot (WB), ELISA (EIA), Flow Cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This CE164 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 246-274 amino acids from the N-terminal region of human CE164. Plays a role in microtubule organization and/or maintenance for the formation of primary cilia (PC), a microtubule-based structure that protrudes from the surface of epithelial cells. Plays a critical role in G2/M checkpoint and nuclear divisions. A key player in the DNA damage-activated ATR/ATM signaling cascade since it is required for the proper phosphorylation of H2AX, RPA,CHK2 and CHK1. Plays a critical role in chromosome segregation, acting as a mediator required for the maintenance of genomic stability through modulation of MDC1, RPA and CHK1. |
Immunogen | n/a |
Other Names | [Centrosomal protein of 164 kDa; Cep164; CEP164; KIAA1052; NPHP15] |
Gene, Accession # | [CEP164], Gene ID: 22897, NCBI: NP_001258862.1, UniProt: Q9UPV0 |
Catalog # | MBS9208297 |
Price | $165, $370 |
Order / More Info | CE164 (N-term), 246-274 Antibody from MYBIOSOURCE INC. |
Product Specific References | Pan, Y.R., et al. Cell Cycle 8(4):655-664(2009) Sivasubramaniam, S., et al. Genes Dev. 22(5):587-600(2008) Graser, S., et al. J. Cell Biol. 179(2):321-330(2007) Petretti, C., et al. EMBO Rep. 7(4):418-424(2006) Zick, A., et al. Nucleic Acids Res. 33(13):4235-4242(2005) |