Edit |   |
---|---|
Antigenic Specificity | MEKKK 4 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of total MEKKK 4 protein. Serine/threonine kinase that may play a role in the response to environmental stress and cytokines such as TNF-alpha. Appears to act upstream of the JUN N-terminal pathway. Phosphorylates SMAD1 on Thr-322.Yao Z., J. Biol. Chem. 274:2118-2125(1999).Wright J.H., Mol. Cell. Biol. 23:2068-2082(2003).Ishikawa K., DNA Res. 5:169-176(1998). |
Immunogen | Immunogen Type: Peptide Immunogen Description: Synthesized peptide derived from internal of human MEKKK 4. |
Other Names | [EC 2.7.11.1; HPK/GCK-like kinase HGK; M4K4; MAP4K4; MAPK/ERK kinase kinase kinase 4] |
Gene, Accession # | [MEKKK 4], Gene ID: 9448, NCBI: NP_001229488.1, UniProt: O95819 |
Catalog # | MBS9403531 |
Price | $200, $255 |
Order / More Info | MEKKK 4 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |