Ubiquitin-like protein ISG15 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityUbiquitin-like protein ISG15
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatcaprylic acid ammonium sulfate precipitate
Size0.1 mL
Concentration1.0 mg/ml
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC)
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DescriptionThe antibody detects endogenous level of total Ubiquitin-like protein ISG15 polyclonal antibody. Ubiquitin-like protein that is conjugated to intracellular target proteins after IFN-alpha or IFN-beta stimulation. Its enzymatic pathway is partially distinct from that of ubiquitin, differing in substrate specificity and interaction with ligating enzymes. ISG15 conjugation pathway uses a dedicated E1 enzyme, but seems to converge with the Ub conjugation pathway at the level of a specific E2 enzyme.Targets include STAT1, SERPINA3G/SPI2A, JAK1, MAPK3/ERK1, PLCG1, EIF2AK2/PKR, MX1/MxA, and RIG-1. Deconjugated by USP18/UBP43. Shows specific chemotactic activity towards neutrophils and activates them to induce release of eosinophil chemotactic fact
ImmunogenImmunogen: Recombinant Human Ubiquitin-like protein ISG15 protein
Other Names[G1P2; UCRP; ISG15; Interferon-induced 15 kDa protein Interferon-induced 17 kDa protein IP17 Ubiquitin cross-reactive protein hUCRP]
Gene, Accession #Gene ID: 9636, NCBI: NP_005092.1, UniProt: P05161
Catalog #MBS9415468
Price$320
Order / More InfoUbiquitin-like protein ISG15 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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