CCN1 Antibody from MYBIOSOURCE INC.
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|---|---|
| Antigenic Specificity | CCN1 |
| Clone | polyclonal |
| Host Species | n/a |
| Reactive Species | human, rat |
| Isotype | n/a |
| Format | immunogen affinity purified |
| Size | 0.1 mg |
| Concentration | n/a |
| Applications | Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Description: Rabbit IgG polyclonal antibody for Protein CYR61(CYR61) detection. Tested with WB in Human;Rat. Background: Cysteine-rich angiogenic inducer 61 (CYR61) or CCN family member 1 (CCN1), is a matricellular protein that in humans is encoded by the CYR61 gene. CYR61 is a secreted, extracellular matrix (ECM)-associated signaling protein of the CCN family (CCN intercellular signaling protein). And it is capable of regulating a broad range of cellular activities, including cell adhesion, migration, proliferation, differentiation, apoptosis, and senescence through interaction with cell surface integrin receptors and heparan sulfate proteoglycans. During embryonic development, CYR61 is critical for cardiac septal morphogenesis, blood vess |
| Immunogen | Immunogen: E Coli-derived human CCN1 recombinant protein (Position: K54-D381). Human CCN1 shares 91.8% and 92.1% amino acid (aa) sequence identity with mouse and rat CCN1, respectively. Ig Type: Rabbit IgG |
| Other Names | [Protein CYR61; 3CH61; CCN 1; CCN family member 1; CCN1; CCN1; CYR 61; Cyr61; CYR61 protein; CYR61 protein precursor; CYR61 protein precursor; CYR61_HUMAN; Cysteine rich angiogenic inducer 61; Cysteine rich angiogenic inducer 61; Cysteine rich angiogenic inducer 61; Cysteine rich heparin binding protein 61; Cysteine-rich angiogenic inducer 61; GIG 1; GIG1; GIG1 protein; GIG1 protein; IBP-10; IGF-binding protein 10; Igfbp 10; IGFBP-10; IGFBP10; IGFBP10; Insulin like growth factor binding protein 10; Insulin like growth factor binding protein 10; Insulin like growth factor binding protein 10; Insulin-like growth factor-binding protein 10; Protein CYR61; Protein GIG1; cysteine-rich, angiogenic inducer, 61], [CYR61; CYR61; CCN1; GIG1; IGFBP10; CCN1; GIG1; IGFBP10; IBP-10; IGF-binding protein 10; IGFBP-10] |
| Gene, Accession # | [CCN1], Gene ID: 3491, NCBI: NP_001545.2, UniProt: O00622 |
| Catalog # | MBS178382 |
| Price | $280 |
| Order / More Info | CCN1 Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Lau LF (October 2011). CCN1/CYR61: the very model of a modern matricellular protein. Cell. Mol. Life Sci. 68 (19): 3149-63. 2. Jay P, Berge-Lefranc JL, Marsollier C, Mejean C, Taviaux S, Berta P (May 1997). The human growth factor-inducible immediate early gene, CYR61, maps to chromosome 1p. Oncogene 14 (14): 1753-7. 3. Jun JI, Lau LF (December 2011). Taking aim at the extracellular matrix: CCN proteins as emerging therapeutic targets. Nature Reviews Drug Discovery 10 (12): 945-63. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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