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Antigenic Specificity | MYLK (Phospho Tyr464) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Immunohistochemistry (IHC) Paraffin, ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Phospho-MYLK (Y464) Polyclonal Antibody detects endogenous levels of MYLK protein only when phosphorylated at Y464. MYLK, a muscle member of the immunoglobulin gene superfamily, encodes myosin light chain kinase which is a calcium/calmodulin dependent enzyme. This kinase phosphorylates myosin regulatory light chains to facilitate myosin interaction with actin filaments to produce contractile activity. MYLK encodes both smooth muscle and nonmuscle isoforms. In addition, using a separate promoter in an intron in the 3' region, it encodes telokin, a small protein identical in sequence to the C-terminus of myosin light chain kinase, that is independently expressed in smooth muscle and functions to stabilize unphosphorylated myosin |
Immunogen | Immunogen: Synthesized peptide derived from human MYLK around the phosphorylation site of Y464 |
Other Names | [Rabbit MYLK (phospho Tyr464); MYLK; MLCK; MLCK1; MYLK1; Myosin light chain kinase; smooth muscle; MLCK; smMLCK; Kinase-related protein; KRP; Telokin] |
Gene, Accession # | [MYLK], Gene ID: 4638, NCBI: NP_444253.3, UniProt: Q15746 |
Catalog # | MBS9705949 |
Price | $130, $220, $325 |
Order / More Info | MYLK (Phospho Tyr464) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |