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Antigenic Specificity | HLA-DQA1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Immunohistochemistry (IHC) Paraffin, ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of HLA-DQA1. HLA-DQA1 belongs to the HLA class II alpha chain paralogues. The class II molecule is a heterodimer consisting of an alpha (DQA) and a beta chain (DQB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: b Lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa. It is encoded by 5 exons; exon 1 encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, and exon 4 encodes the transmembrane domain and the cytoplasmic tail. Within the DQ molecule both the alpha chain and the beta chain contai |
Immunogen | Immunogen: Synthesized peptide derived from part region of human HLA-DQA1 protein at amino acid sequence of 21-70 |
Other Names | [Rabbit HLA-DQA1; HLA class II histocompatibility antigen, DQ alpha 1 chain; DC-1 alpha chain; DC-alpha; HLA-DCA; MHC class II DQA1] |
Gene, Accession # | [HLA-DQA1], Gene ID: 3117, NCBI: P01909.1, UniProt: P01909 |
Catalog # | MBS9709369 |
Price | $130, $220, $325 |
Order / More Info | HLA-DQA1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |