GFR a-2 (IN) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityGFR a-2 (IN)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatimmunoaffinity purified
Size0.1 mg
Concentrationn/a
ApplicationsWestern Blot (WB)
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DescriptionMembers of the glial cell line-derived neurotrophic factor (GDNF) family, including GDNF and neurturin (NTN), play key roles in the control of vertebrate neuron survival and differentiation. Physiological responses to NTN require the presence of a novel glycosylphosphadidylinositol linked protein NTNRα, which is a cell surface receptor for NTN. The cDNAs encoding NTNRa from human, rat, chicken, and mouse have been cloned recently. NTNRα was also termed GDNFRβ, Ret ligand 2 (RETL2) or TGFβ-related neurotrophic factor receptor 2 (TrnR2) and nominated as GFRα-2 recently. GFRα-2 binds NTN and mediates activation of RET receptor tyrosine kinase by both NTN and GDNF. Thus, NTN, GFRα-2, and the Ret PTK form a com
ImmunogenImmunogen: Peptide corresponding to amino acids 377 to 391 of human GFRalpha;-2. The amino acid sequences of immunogenic peptide are identical to those of mouse and rat.
Other Names[GDNFRb (IN); GDNFRbeta (IN); Neurturin receptor alpha; RET ligand 2], [GFRA2; GFRA2; NTNRA; RETL2; TRNR2; GDNFRB; NRTNR-ALPHA; GDNFRB; RETL2; TRNR2; GDNF receptor alpha-2; GDNFR-alpha-2; GFR-alpha-2; GDNFR-beta; NRTNR-alpha; NTNR-alpha]
Gene, Accession #[GFR a-2], Gene ID: 2675, NCBI: NP_001158510.1, UniProt: O00451
Catalog #MBS395934
Price$510
Order / More InfoGFR a-2 (IN) Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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