POLR3E Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityPOLR3E
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatpeptide affinity purified
Size0.1 mL, 0.2 mL
Concentration1mg/ml
ApplicationsWestern Blot (WB), ELISA (EIA)
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DescriptionSpecificity: POLR3E antibody detects endogenous levels of total POLR3E. Function: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. Essential for efficient transcription from both the type 2 VAI and type 3 U6 RNA polymerase III promoters. Plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses. Acts as nuclear and cytosolic DNA sensor involved in innate immune response. Can sense non-self dsDNA that serves as template for transcription into dsRNA. The non-self RNA polymerase III transcripts, such as Epstein-Barr viru
ImmunogenImmunogen: A synthesized peptide derived from human POLR3E Subcellular Location: Nuclear Predicted Cross Reactivity: Pig, Bovine, Horse, Sheep, Rabbit, Dog Similarity: Pig (100%), Bovine (100%), Horse (100%), Sheep (100%), Rabbit (90%), Dog (80%)
Other Names[DNA directed RNA polymerase III 80 kDa polypeptide; DNA-directed RNA polymerase III subunit RPC5; FLJ10509; KIAA1452; polymerase (RNA) III (DNA directed) polypeptide E (80kD); Polymerase (RNA) III (DNA directed) polypeptide E; RNA polymerase III 80 kDa subunit RPC5; RNA polymerase III subunit C5; RPC5; SIN]
Gene, Accession #[POLR3E], Gene ID: 55718, NCBI: NP_001244962.1, UniProt: Q9NVU0
Catalog #MBS9602209
Price$240, $280
Order / More InfoPOLR3E Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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