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Antigenic Specificity | POLR3E |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: POLR3E antibody detects endogenous levels of total POLR3E. Function: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. Essential for efficient transcription from both the type 2 VAI and type 3 U6 RNA polymerase III promoters. Plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses. Acts as nuclear and cytosolic DNA sensor involved in innate immune response. Can sense non-self dsDNA that serves as template for transcription into dsRNA. The non-self RNA polymerase III transcripts, such as Epstein-Barr viru |
Immunogen | Immunogen: A synthesized peptide derived from human POLR3E Subcellular Location: Nuclear Predicted Cross Reactivity: Pig, Bovine, Horse, Sheep, Rabbit, Dog Similarity: Pig (100%), Bovine (100%), Horse (100%), Sheep (100%), Rabbit (90%), Dog (80%) |
Other Names | [DNA directed RNA polymerase III 80 kDa polypeptide; DNA-directed RNA polymerase III subunit RPC5; FLJ10509; KIAA1452; polymerase (RNA) III (DNA directed) polypeptide E (80kD); Polymerase (RNA) III (DNA directed) polypeptide E; RNA polymerase III 80 kDa subunit RPC5; RNA polymerase III subunit C5; RPC5; SIN] |
Gene, Accession # | [POLR3E], Gene ID: 55718, NCBI: NP_001244962.1, UniProt: Q9NVU0 |
Catalog # | MBS9602209 |
Price | $240, $280 |
Order / More Info | POLR3E Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |