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Antigenic Specificity | Bax |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | rat, mouse |
Isotype | n/a |
Format | serum |
Size | 0.05 mL |
Concentration | n/a |
Applications | Immunoprecipitation (IP), Immunohistochemistry (IHC) Formalin/Paraffin, Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This antibody reacts with Bax isoforms containing the peptide immunogen sequence (PELTLEQPPQDASTKKLS). Mouse and rat Bax alpha are 192 amino acid proteins. The Bcl-2 family of apoptosis-related genes plays central roles in regulating apoptotic pathways. Regulation of cell death through apoptosis is critical for the maintenance of homeostasis, defense against infectious agents, and normal development. Bcl-2 family proteins regulate apoptosis primarily through the regulation of mitochondrial outer membrane permeability. In mammals, Bcl-2 family proteins can be divided into 3 main subfamilies on the basis of their function and the content of their Bcl-2 homology (BH) domains, for example: 1) Prosurvival: Bcl-2, Bcl-XL, Bcl-W, A1, and Mcl-1 2) |
Immunogen | Immunogen Information: A synthetic peptide of Bax protein (amino acids 43-60 PELTLEQPPQDASTKKLS) was used as the immunogen for this antibody |
Other Names | [BAX; BCL2L4; Bcl-2-like protein 4; to Bax; Bax; Bax], [BAX; BAX; BCL2L4; BCL2L4; Bcl2-L-4] |
Gene, Accession # | [BAX], Gene ID: 581, NCBI: Q07812.1, UniProt: Q07812 |
Catalog # | MBS668533 |
Price | $270 |
Order / More Info | Bax Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |