HSP60 (Heat Shock Protein 60) (Mitochondrial Marker) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityHSP60 (Heat Shock Protein 60) (Mitochondrial Marker)
Clone[rGROEL/780]
Host SpeciesMouse
Reactive Specieshuman, mouse, rat, hamster, sheep, rabbit, cow, dog, porcine, monkey, chicken, Xenopus laevis, Drosophila.does not react with Bacteria, Helminths, Spinach.
IsotypeIgG1, kappa
Formatunconjugated
Size0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA at 1mg/ml)
Concentrationn/a
ApplicationsFlow Cytometry (FC/FACS), Immunofluorescence (IF), Western Blot (WB), Immunohistochemistry (IHC) Formalin
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DescriptionRecognizes a 60kDa protein, identified as the heat shock protein 60 (hsp60). Its epitope is localized between aa 383-447 of human hsp60. A wide variety of environmental and pathophysiological stressful conditions trigger the synthesis of a family of proteins known as heat shock proteins (hsp s), more appropriately called as stress response proteins (srp s). hsp60 is a potential antigen in a number of autoimmune diseases. In human arthritis and in experimentally induced arthritis in animals, disease development coincides with the development of immune reactivity directed against not only bacterial hsp60, but also against its mammalian homolog. Clone rGROEL/780, unlike LK2, recognizes only the mammalian (not bacterial) hsp60 and is useful in
ImmunogenImmunogen: Recombinant full-length human HSP60 protein Cellular Localization: Mitochondria in Cytoplasm
Other Names[60kDa chaperonin, 60kDa heat shock protein mitochondrial, Chaperonin, 60-KD (CPN60), GROEL, HLD4, HSP65, HSPD1, HuCHA60, Mitochondrial matrix protein P1, P60 lymphocyte protein, Short heat shock protein 60 Hsp60s1, Spastic paraplegia 13 (SPG13)]
Gene, Accession #[HSP60], Gene ID: 3329, NCBI: NP_002147.2, UniProt: P10809
Catalog #MBS4380026
Price$190, $340, $340
Order / More InfoHSP60 (Heat Shock Protein 60) (Mitochondrial Marker) Antibody from MYBIOSOURCE INC.
Product Specific ReferencesBoog CJ; de Graeff-Meeder ER; Lucassen MA; van der Zee R; Voorhorst-Ogink MM; van Kooten PJ; Geuze HJ; van Eden W. Two monoclonal antibodies generated against human hsp60 show reactivity with synovial membranes of patients with juvenile chronic arthritis. Journal of Experimental Medicine, 1992, 175(6):1805-10.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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