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Antigenic Specificity | CASP3 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mg |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Western blot analysis of extracts of Jurkat cell Line, using CASP3 antibody. Caspase-3 (CPP-32, Apoptain, Yama, SCA-1) is a critical executioner of apoptosis, as it is either partially or totally responsible for the proteolytic cleavage of many key proteins such as the nuclear enzyme poly (ADP-ribose) polymerase (PARP) (1). Activation of caspase-3 requires proteolytic processing of its inactive zymogen into activated p17 and p12 fragments. Cleavage of caspase-3 requires aspartic acid at the P1 position (2). |
Immunogen | Immunogen: Recombinant protein of human CASP3 |
Other Names | [casp3 protein; casp3 protein], [casp3] |
Gene, Accession # | [CASP3], Gene ID: 100653443, NCBI: NP_001233264.1 |
Catalog # | MBS419384 |
Price | $385 |
Order / More Info | CASP3 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |