IL-6, Mouse Antibody from MYBIOSOURCE INC.
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|---|---|
| Antigenic Specificity | IL-6, Mouse |
| Clone | MP5-20F3 |
| Host Species | Rat |
| Reactive Species | mouse |
| Isotype | IgG1 |
| Format | unconjugated |
| Size | 0.1 mg, 0.5 mg |
| Concentration | n/a |
| Applications | FS, Immunoassay (IA), Immunoprecipitation (IP) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Product Description: The antibody neutralizes mouse interleukin 6 (IL-6). It does not cross-react with LPS (the component of the bacterial cell wall which is considered responsible for the toxicity of gram-negative bacteria) and TNF-alpha nor does it bind to either human or rat IL-6. The antibody inhibits IL-6 induced proliferation of the B9 assay. IL-6 is a pluripotent 20-22 kDa cytokine which plays a role in the pathophysiology of severe infection and regulates the immune response, acute phase reaction and haematopoiesis. IL-6 plays a critical role in B-cell differentiation to plasma cells and is a potent growth factor for plasmacytoma and myeloma. Continuous IL-6 gene expression makes an essential contribution to a multistep oncogenesis |
| Immunogen | n/a |
| Other Names | [Interleukin-6; Interleukin-6; interleukin-6; CDF; BSF-2; IFN-beta-2; interferon beta-2; interleukin BSF-2; interferon, beta 2; hybridoma growth factor; CTL differentiation factor; B-cell stimulatory factor 2; B-cell differentiation factor; interleukin 6; B-cell stimulatory factor 2; BSF-2; CTL differentiation factor; CDF; Hybridoma growth factor; Interferon beta-2; IFN-beta-2], [IL6; IL6; HGF; HSF; BSF2; IL-6; IFNB2; IFNB2; IL-6; BSF-2; CDF; IFN-beta-2] |
| Gene, Accession # | [IL-6], Gene ID: 3569, NCBI: P05231.1 |
| Catalog # | MBS584262 |
| Price | $375, $950 |
| Order / More Info | IL-6, Mouse Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Takatsuki, F et al; Human recombinant IL-6/B cell stimulatory factor 2 augments murine antigen-specific antibody responses in vitro and in vivo. J Immunol 1988, 141: 3072 2. McKenzie, D et al; Alloantigen presentation by B cells. Requirement for IL-1 and IL-6. J Immunol 1988, 141: 2907 3. van Snick, J et al; Interleukin-6: an overview. Annu Rev Immunol 1990, 8: 253 4. Heinrich, PC et al; Interleukin-6 and the acute phase response. Biochem J 1990, 265: 621 5. Starnes, HF Jr et al; Anti-IL-6 monoclonal antibodies protect against lethal Escherichia coli infection and lethal tumor necrosis factor-alpha challenge in mice. J Immunol 1990, 145: 4185 6. Hirano, T et al; Interleukin 6 (IL-6) and its receptor: their role in plasma cell neoplasias. Int J Cell Cloning 1991, 9: 166 7. Hooghe-Peters, E et al; Interleukin-1, interleukin-6: messengers in the neuroendocrine immune system? Pathol Res Pract 1991, 187: 622 |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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